2407957-87-1

EGFR-IN-8 Chemical Structure
2407957-87-1

Chemical Structure

EGFR-IN-8

  • CAS No.: 2407957-87-1
  • Formula:C32H23ClF3N7O4
  • Molecular Weight:662.02

IUPAC Name: N-(3-chloro-4-(5-(3-(3-(4-(cyclopropanecarboxamido)-3-(trifluoromethyl)phenyl)ureido)phenyl)-1,2,4-oxadiazol-3-yl)phenyl)nicotinamide

InChIKey: IIUNSVLRVWGJRM-UHFFFAOYSA-N

SMILES: O=C(NC1=CC(C(F)(F)F)=C(NC(C2CC2)=O)C=C1)NC3=CC=CC(C4=NC(C5=CC=C(NC(C6=CC=CN=C6)=O)C=C5Cl)=NO4)=C3

Biological Activity: EGFR-IN-8 is a dual EGFR and c-Met inhibitor, compound 48. EGFR-IN-8 can be a promising candidate for further development to target EGFR TKI-resistant NSCLC[1].

Cat. No. Product Name Purity Description Pricing
HY-126320
EGFR-IN-8 98.01% EGFR-IN-8 is a dual EGFR and c-Met inhibitor, compound 48. EGFR-IN-8 can be a promising candidate for further development to target EGFR TKI-resistant NSCLC.
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