2421117-98-6
2421117-98-6
Chemical Structure
BC-DXI-843
- CAS No.: 2421117-98-6
- Formula:C28H26N4O4S2
- Molecular Weight:546.66
IUPAC Name: (S)-3-(1H-indol-3-yl)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-2-((4-methylphenyl)sulfonamido)propanamide
InChIKey: VLPGAOXBMXGNGM-VWLOTQADSA-N
SMILES: COC(C=C1)=CC=C1C2=CSC(NC([C@@H](NS(C3=CC=C(C)C=C3)(=O)=O)CC4=CNC5=C4C=CC=C5)=O)=N2
Biological Activity: BC-DXI-843 is a potent and specific AIMP2-DX2 inhibitor with an IC50 of 0.92 μM, more than 100-fold selectivity over AIMP2 (IC50 >100 μM) in a luciferase assay. BC-DXI-843 acts as a promising lead targeting AIMP2-DX2 in lung cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BC-DXI-843 | 99.76% | BC-DXI-843 is a potent and specific AIMP2-DX2 inhibitor with an IC50 of 0.92 μM, more than 100-fold selectivity over AIMP2 (IC50 >100 μM) in a luciferase assay. BC-DXI-843 acts as a promising lead targeting AIMP2-DX2 in lung cancer. | ||||||||||||||||||||
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References
Keywords
