253678-67-0
Chemical Structure
n-Undecyl β-D-maltopyranoside
- CAS No.: 253678-67-0
- Formula:C23H44O11
- Molecular Weight:496.59
IUPAC Name: (2R,3R,4S,5S,6R)-2-(((2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-(undecyloxy)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
InChIKey: UYEMNFYVTFDKRG-ZNGNCRBCSA-N
SMILES: CCCCCCCCCCCO[C@H]1[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O[C@@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)O)O
Biological Activity: n-Undecyl β-D-maltopyranoside is an n-alkyl β-D-maltopyranoside detergent that can be used for solubilization and structural determination of membrane proteins. n-Undecyl β-D-maltopyranoside effectively solubilizes CST from Golgi-enriched fractions of Pichia pastoris, but fails to maintain the functional activity of CST during subsequent partial purification and reconstitution into proteoliposomes. n-Undecyl β-D-maltopyranoside is more suitable for structural analysis studies of membrane proteins rather than functional reconstitution experiments[1][2].
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n-Undecyl β-D-maltopyranoside | n-Undecyl β-D-maltopyranoside is an n-alkyl β-D-maltopyranoside detergent that can be used for solubilization and structural determination of membrane proteins. n-Undecyl β-D-maltopyranoside effectively solubilizes CST from Golgi-enriched fractions of Pichia pastoris, but fails to maintain the functional activity of CST during subsequent partial purification and reconstitution into proteoliposomes. n-Undecyl β-D-maltopyranoside is more suitable for structural analysis studies of membrane proteins rather than functional reconstitution experiments. | |||||||||||||||||||||
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References
- [1]. Maggioni A, et al. Expression, solubilisation, and purification of a functional CMP-sialic acid transporter in Pichia pastoris. Protein Expr Purif. 2014;101:165-171. [Content Brief]
- [2]. Cho K H, et al. Maltose neopentyl glycol-3 (MNG-3) analogues for membrane protein study[J]. Analyst, 2015, 140(9): 3157-3163.
