2573901-15-0
2573901-15-0
Chemical Structure
JADA3
- CAS No.: 2573901-15-0
- Formula:C10H10ClN3O2
- Molecular Weight:239.66
IUPAC Name: 5-chloro-6-isopropyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbaldehyde
InChIKey: ZLWGJAFBBMOOFV-UHFFFAOYSA-N
SMILES: O=CC=1C=NN2C(=O)C(=C(Cl)NC12)C(C)C
Biological Activity: JADA3 is a molecular glue degrader targeting IKZF1 and IKZF3. JADA3 induces proteasome-mediated degradation of the target transcription factors by binding to the E3 ubiquitin ligase Cereblon. JADA3 can be used in research related to acute myeloid leukemia[1].
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JADA3 | JADA3 is a molecular glue degrader targeting IKZF1 and IKZF3. JADA3 induces proteasome-mediated degradation of the target transcription factors by binding to the E3 ubiquitin ligase Cereblon. JADA3 can be used in research related to acute myeloid leukemia. | |||||||||||||||||||||
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