2588445-14-9
2588445-14-9
Chemical Structure
TREX1-IN-4
- CAS No.: 2588445-14-9
- Formula:C24H19ClN6O4
- Molecular Weight:490.90
InChIKey: XIPPVDDDFIARFV-FQEVSTJZSA-N
SMILES: CN(C1=NC(C(NC2=CON=C2)=O)=C(C(N1C)=O)O)[C@H](C3=C(C=CC=C3)Cl)C4=CC(C#N)=CC=C4
Biological Activity: TREX1-IN-4 (Compound 96) is an inhibitor of both TREX1 and TREX2, with an IC50 for TREX1 of less than 0.1 μM, an IC50 for TREX2 of less than 1 μM, and an EC50 for HCT116 cells ranging from 0.1 to 10 μM. TREX1-IN-4 can be used in cancer research[1].
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TREX1-IN-4 | TREX1-IN-4 (Compound 96) is an inhibitor of both TREX1 and TREX2, with an IC50 for TREX1 of less than 0.1 μM, an IC50 for TREX2 of less than 1 μM, and an EC50 for HCT116 cells ranging from 0.1 to 10 μM. TREX1-IN-4 can be used in cancer research. | |||||||||||||||||||||
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