2760354-12-7
Chemical Structure
KRAS G12C inhibitor 50
- CAS No.: 2760354-12-7
- Formula:C31H34N8O2
- Molecular Weight:550.65
IUPAC Name: 2-((S)-1-acryloyl-4-(2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-7-(naphthalen-1-ylmethyl)imidazo[2,1-f][1,2,4]triazin-4-yl)piperazin-2-yl)acetonitrile
InChIKey: OMJLVKOHXNQCJC-DQEYMECFSA-N
SMILES: C=CC(N1CCN(C[C@@H]1CC#N)C2=NC(OC[C@@H]3CCCN3C)=NN4C(CC5=C6C=CC=CC6=CC=C5)=CN=C24)=O
Biological Activity: KRAS G12C inhibitor 50 (Example 4) is a KRAS G12C inhibitor with an IC50 of 46.7 nM[1].
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KRAS G12C inhibitor 50 | KRAS G12C inhibitor 50 (Example 4) is a KRAS G12C inhibitor with an IC50 of 46.7 nM. | |||||||||||||||||||||
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Keywords