2767219-19-0
Chemical Structure
(S,R,S)-Ahpc-PEG6-azide
- CAS No.: 2767219-19-0
- Formula:C37H57N7O10S
- Molecular Weight:791.95
IUPAC Name: (2R,4S)-1-((S)-1-azido-23-(tert-butyl)-21-oxo-3,6,9,12,15,18-hexaoxa-22-azatetracosan-24-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChIKey: VLTOMOCVFZUMRW-BEJSXWRTSA-N
SMILES: [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCC(N[C@@H](C(C)(C)C)C(N1[C@H](C[C@@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O
Biological Activity: (S, R, S)-AHPC-PEG6-Azide is a click chemistry PROTAC linker that incorporates an E3 ligase ligand with a PEG6 arm to empower PROTAC research & discovery. The hydrophilic PEG spacer increases the solubility of a compound in aqueous media. Azide enables click chemistry with alkyne, DBCO, or BCN molecule.
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(S,R,S)-Ahpc-PEG6-azide | (S, R, S)-AHPC-PEG6-Azide is a click chemistry PROTAC linker that incorporates an E3 ligase ligand with a PEG6 arm to empower PROTAC research & discovery. The hydrophilic PEG spacer increases the solubility of a compound in aqueous media. Azide enables click chemistry with alkyne, DBCO, or BCN molecule. | |||||||||||||||||||||
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