2768139-76-8
2768139-76-8
Chemical Structure
ErSO-DFP
- CAS No.: 2768139-76-8
- Formula:C20H17F5N2O2
- Molecular Weight:412.35
IUPAC Name: (R)-3-(4,4-difluoropiperidin-1-yl)-3-(4-hydroxyphenyl)-7-(trifluoromethyl)indolin-2-one
InChIKey: IVIIASPFEXRZGM-LJQANCHMSA-N
SMILES: O=C1NC2=C(C=CC=C2[C@]1(N3CCC(F)(CC3)F)C4=CC=C(C=C4)O)C(F)(F)F
Biological Activity: ErSO-DFP is an anticipatory unfolded protein response (a-UPR) activator. ErSO-DFP has enhanced selectivity for estrogen receptor alpha-positive (ERα+) cancer cells with a wider selectivity window than ErSO (HY-132247). ErSO-DFP displays antitumor activity against MCF-7 in mice. ErSO-DFP can cross the blood brain barrier[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ErSO-DFP | 99.56% | ErSO-DFP is an anticipatory unfolded protein response (a-UPR) activator. ErSO-DFP has enhanced selectivity for estrogen receptor alpha-positive (ERα+) cancer cells with a wider selectivity window than ErSO (HY-132247). ErSO-DFP displays antitumor activity against MCF-7 in mice. ErSO-DFP can cross the blood brain barrier. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
