2803422-60-6
2803422-60-6
Chemical Structure
MTH1 activator-1
- CAS No.: 2803422-60-6
- Formula:C29H23F3N4O2
- Molecular Weight:516.51
SMILES: O=C(C1=NC=C(C=C1)C#CC2=CC=CC3=C2C=CN=C3)NC4=CC=C(CN5CCOCC5)C(C(F)(F)F)=C4
Biological Activity: MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. MTH1 activator-1 can be used to probe the cellular and biological effects of upregulated oxidative damage repair in nucleotide pools and to delay or abrogate tumorigenesis[1].
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MTH1 activator-1 | 98.18% | MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. MTH1 activator-1 can be used to probe the cellular and biological effects of upregulated oxidative damage repair in nucleotide pools and to delay or abrogate tumorigenesis. | ||||||||||||||||||||
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