2938179-13-4
Chemical Structure
KRAS G12D-IN-27
- CAS No.: 2938179-13-4
- Formula:C34H33F3N8OS
- Molecular Weight:658.74
InChIKey: KJKCCORYSXGAFS-QNGMFEMESA-N
SMILES: N#CC1=CC2=C(N3CC(N4)CCC4C3)N=C(OCC5(CN6C[C@H](F)CC6)CCC5)N=C2C(F)=[C@]1[C@]7=C(C(C#N)=C(N)S8)C8=C(F)C=C7
Biological Activity: KRAS G12D-IN-27 (H12a) is an inhibitor of KRAS G12D. KRAS G12D-IN-27 inhibits ERK phosphorylation, with an IC50 of 112 nM. KRAS G12D-IN-27 can be used in cancer research[1].
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KRAS G12D-IN-27 | KRAS G12D-IN-27 (H12a) is an inhibitor of KRAS G12D. KRAS G12D-IN-27 inhibits ERK phosphorylation, with an IC50 of 112 nM. KRAS G12D-IN-27 can be used in cancer research. | |||||||||||||||||||||
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Keywords