3029898-85-6
3029898-85-6
Chemical Structure
MerTK-IN-3
- CAS No.: 3029898-85-6
- Formula:C36H31FN8O4
- Molecular Weight:658.68
InChIKey: WOAZQVRBSBTOAN-UHFFFAOYSA-N
SMILES: O=C(C1=CN(C)N(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=C5C(OC(C6=CN(C)N=C6)=C5C7=CC=CC(CN(C)C)=C7)=NC=N4)C=C3
Biological Activity: MerTK-IN-3 (compound 11) is an orally active and selectivity MerTK inhibitor with IC50 values of 21.5 nM and 991.3 nM for MerTK and Tyro3, respectively. MerTK-IN-3 can be used for study of colon cancer[1].
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MerTK-IN-3 | MerTK-IN-3 (compound 11) is an orally active and selectivity MerTK inhibitor with IC50 values of 21.5 nM and 991.3 nM for MerTK and Tyro3, respectively. MerTK-IN-3 can be used for study of colon cancer. | |||||||||||||||||||||
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