3032232-47-3
3032232-47-3
Chemical Structure
TLX agonist 3
- CAS No.: 3032232-47-3
- Formula:C25H23F3N4O2
- Molecular Weight:468.48
IUPAC Name: 2-butoxy-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)quinoline-4-carboxamide
InChIKey: RTKBIHCZDFXHLC-UHFFFAOYSA-N
SMILES: O=C(NC=1C=C(C=C(C1)C(F)(F)F)N2C=NC(=C2)C)C=3C=C(N=C4C=CC=CC43)OCCCC
Biological Activity: TLX agonist 3 is a potent and selective tailless homolog (TLX, NR2E1) agonist with an EC50 of 0.25 μM and a Kd of 1.6 μM). TLX agonist 3 shows high selectivity over related nuclear receptors, and promotes TLX oligomerization with an EC50 of 5.0 μM. TLX agonist 3 can be used for the research of neurodegenerative diseases[1].
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TLX agonist 3 | TLX agonist 3 is a potent and selective tailless homolog (TLX, NR2E1) agonist with an EC50 of 0.25 μM and a Kd of 1.6 μM). TLX agonist 3 shows high selectivity over related nuclear receptors, and promotes TLX oligomerization with an EC50 of 5.0 μM. TLX agonist 3 can be used for the research of neurodegenerative diseases. | |||||||||||||||||||||
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