3037125-72-4
3037125-72-4
Chemical Structure
CD27 peptide
- CAS No.: 3037125-72-4
- Formula:C54H92N18O17S3
- Molecular Weight:1361.61
InChIKey: NTQJQNCIMQXRTJ-PRJXXBLISA-N
SMILES: O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CS)C(N[C@@H](CC(O)=O)C(N1[C@@H](CCC1)C(N[C@@H](CS)C(N[C@@H]([C@@H](C)CC)C(N2[C@@H](CCC2)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CS)N
Biological Activity: CD27 peptide is a 13-amino acid peptide derived from CD27. CD27 peptide is a targeting ligand for CD70 and can be used to construct CD70-targeted peptide amphiphile micelles. CD27 peptide can be used for research on melanoma and clear cell renal cell carcinoma[1][2].
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CD27 peptide | CD27 peptide is a 13-amino acid peptide derived from CD27. CD27 peptide is a targeting ligand for CD70 and can be used to construct CD70-targeted peptide amphiphile micelles. CD27 peptide can be used for research on melanoma and clear cell renal cell carcinoma. | |||||||||||||||||||||
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References
- [1]. Trac N, et al. CD70-Targeted Micelles Enhance HIF2α siRNA Delivery and Inhibit Oncogenic Functions in Patient-Derived Clear Cell Renal Carcinoma Cells. Molecules (Basel, Switzerland). 2022 Dec 02;27(23):8457.
- [2]. Riccione KA, et al. CD27 stimulation unveils the efficacy of linked class I/II peptide vaccines in poorly immunogenic tumors by orchestrating a coordinated CD4/CD8 T cell response. Oncoimmunology. 2018 Sep 5;7(12):e1502904.
