3041047-51-9
3041047-51-9
Chemical Structure
PF-07957472
- CAS No.: 3041047-51-9
- Formula:C29H32N6O
- Molecular Weight:480.60
InChIKey: MMVYUHFDLZLNDJ-UHFFFAOYSA-N
SMILES: O=C(C1=CC(N2CCN(CC2)C)=CC=C1C)NC3(CC3)C4=C5C=CC=CC5=NC(C6=CN(C)N=C6)=C4
Biological Activity: PF-07957472 (Compound 4) is an orally active and selective SARS-CoV-2 papain-like protease (PLpro) inhibitor, with a Ki of 2 nM against SARS-CoV-2 PLpro. PF-07957472 reduces SARS-CoV-2 viral titers in the lungs of infected mice and inhibits SARS-CoV-2-induced cytopathic effects in cells. PF-07957472 can be used for the research of COVID-19[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-07957472 | 99.13% | PF-07957472 (Compound 4) is an orally active and selective SARS-CoV-2 papain-like protease (PLpro) inhibitor, with a Ki of 2 nM against SARS-CoV-2 PLpro. PF-07957472 reduces SARS-CoV-2 viral titers in the lungs of infected mice and inhibits SARS-CoV-2-induced cytopathic effects in cells. PF-07957472 can be used for the research of COVID-19. | ||||||||||||||||||||
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References
Keywords
