3104023-24-4
3104023-24-4
Chemical Structure
IL-4-IN-2
- CAS No.: 3104023-24-4
- Formula:C18H14N4O2
- Molecular Weight:318.33
InChIKey: LJCTWPCRPDZTBA-UHFFFAOYSA-N
SMILES: N#CC1=C(N)N=C(C2=CC=C(N)C=C2)C=C1C3=CC(O)=C(O)C=C3
Biological Activity: IL-4-IN-2 (Compound 14/analog 14) is a selective IL-4 inhibitor. IL-4-IN-2 binds to soluble IL-4 and inhibits IL-4-mediated signal transduction. IL-4-IN-2 suppresses STAT-6 phosphorylation induced by IL-13 and IL-4 in monocytes and B lymphocytes. IL-4-IN-2 is applicable to the research of allergic inflammation, cancer, autoimmune diseases, asthma and arthritis[1].
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IL-4-IN-2 | IL-4-IN-2 (Compound 14/analog 14) is a selective IL-4 inhibitor. IL-4-IN-2 binds to soluble IL-4 and inhibits IL-4-mediated signal transduction. IL-4-IN-2 suppresses STAT-6 phosphorylation induced by IL-13 and IL-4 in monocytes and B lymphocytes. IL-4-IN-2 is applicable to the research of allergic inflammation, cancer, autoimmune diseases, asthma and arthritis. | |||||||||||||||||||||
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