3106015-71-5
Chemical Structure
QHL-1618
- CAS No.: 3106015-71-5
- Formula:C66H90FN11O23
- Molecular Weight:1424.48
IUPAC Name: (S)-N1-((7S,10S,13S)-7-(2-amino-2-oxoethyl)-1-(((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)amino)-10-methyl-1,6,9,12-tetraoxo-3-oxa-5,8,11-triazatetradecan-13-yl)-2-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)-N5-(2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)pentanediamide
InChIKey: RJAUINQOVFFVSY-TWXCYVJGSA-N
SMILES: O=C(C=C1)N(C1=O)CCC(N[C@@H](CCC(NCCOCCOCCOCCOCCOCCOCCOCCOC)=O)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(NCOCC(N[C@H]2CCC3=C4C2=C5C(C(N6C5)=CC([C@@](O)(CC)C(OC7)=O)=C7C6=O)=NC4=CC(F)=C3C)=O)=O)=O)=O)=O)=O
Biological Activity: QHL-1618 is a tumor microenvironment-activated drug conjugate. QHL-1618 inhibits the tumor growth in various tumor models, such as HT-1080 xenograft, CT-26 xenograft[1].
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QHL-1618 | QHL-1618 is a tumor microenvironment-activated drug conjugate. QHL-1618 inhibits the tumor growth in various tumor models, such as HT-1080 xenograft, CT-26 xenograft. | |||||||||||||||||||||
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Keywords
