3121040-39-6
Chemical Structure
POLRMT-IN-4
- CAS No.: 3121040-39-6
- Formula:C23H23FN2O4
- Molecular Weight:410.44
InChIKey: ZXMHJWMIBAGBOG-OAHLLOKOSA-N
SMILES: O=C1C=C(C2=CC=CC=C2C)C3=C(O1)C=C(O[C@H](C)C(N4CCNCC4)=O)C(F)=C3
Biological Activity: POLRMT-IN-4 is a photoactivated mitochondrial RNA polymerase (POLRMT) inhibitor. POLRMT-IN-4 can be liberated from the photoactivatable prodrug upon irradiation, enables spatiotemporally precise inhibition and localized tissue selectivity. POLRMT-IN-4 disrupts mitochondrial transcription, impairs oxidative phosphorylation, and suppresses cancer cell proliferation. POLRMT-IN-4 can be used in research on various cancers, such as pancreatic cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
POLRMT-IN-4 | POLRMT-IN-4 is a photoactivated mitochondrial RNA polymerase (POLRMT) inhibitor. POLRMT-IN-4 can be liberated from the photoactivatable prodrug upon irradiation, enables spatiotemporally precise inhibition and localized tissue selectivity. POLRMT-IN-4 disrupts mitochondrial transcription, impairs oxidative phosphorylation, and suppresses cancer cell proliferation. POLRMT-IN-4 can be used in research on various cancers, such as pancreatic cancer. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
