364361-68-2
364361-68-2
Chemical Structure
Endosidine 5
Synonym(s): ES5
- CAS No.: 364361-68-2
- Formula:C20H18N4
- Molecular Weight:314.38
InChIKey: LNOMKSXDSWKSNE-WSDLNYQXSA-N
SMILES: CC1=CC=C2C=C(C(N/N=C/C3=CNC4=C3C=CC=C4)=NC2=C1)C
Biological Activity: Endosidine 5 (ES5) inhibits EPS (extracellular polymeric substance) secretion and cell wall expansion. Endosidine 5 alters secretion of ECM (extracellular matrix) material in Penium margaritaceum by affecting the Golgi apparatus. Endosidine 5 interferes with recycling endosomes through Annexin A6, thereby promoting the release and expression of mRNA into the cytoplasm[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Endosidine 5 | 99.80% | Endosidine 5 (ES5) inhibits EPS (extracellular polymeric substance) secretion and cell wall expansion. Endosidine 5 alters secretion of ECM (extracellular matrix) material in Penium margaritaceum by affecting the Golgi apparatus. Endosidine 5 interferes with recycling endosomes through Annexin A6, thereby promoting the release and expression of mRNA into the cytoplasm. | ||||||||||||||||||||
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References
- [1]. LoRicco JG, et al. Endosidin 5 disruption of the Golgi apparatus and extracellular matrix secretion in the unicellular charophyte Penium margaritaceum. Ann Bot. 2023 Jul 10;131(6):967-983. [Content Brief]
- [2]. Shin J, et al. Targeting Recycling Endosomes to Potentiate mRNA Lipid Nanoparticles. Nano Lett. 2024 May 1;24(17):5104-5109. [Content Brief]
