81026-63-3
81026-63-3
Chemical Structure
SC 34301
Synonym(s): Enisoprost
- CAS No.: 81026-63-3
- Formula:C22H36O5
- Molecular Weight:380.52
IUPAC Name: methyl (Z)-7-((1R,2R,3R)-3-hydroxy-2-((E)-4-hydroxy-4-methyloct-1-en-1-yl)-5-oxocyclopentyl)hept-4-enoate
InChIKey: CIBHDGPIOICRGX-ZQCHCGQNSA-N
SMILES: CCCCC(C)(O)C/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CC/C=C\CCC(OC)=O
Biological Activity: SC 34301 (Enisoprost) is a potent and orally active PGE1 analog. SC 34301 significantly reduces bacterial translocation and improves survival for burned mice[1][2].
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SC 34301 | SC 34301 (Enisoprost) is a potent and orally active PGE1 analog. SC 34301 significantly reduces bacterial translocation and improves survival for burned mice. | |||||||||||||||||||||
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References
- [1]. Pollak R, et al. A trial of the prostaglandin E1 analogue, enisoprost, to reverse chronic cyclosporine-associated renal dysfunction. Am J Kidney Dis. 1992 Oct;20(4):336-41. [Content Brief]
- [2]. Fukushima R, et al. The degree of bacterial translocation is a determinant factor for mortality after burn injury and is improved by prostaglandin analogs. Ann Surg. 1992 Oct;216(4):438-44; discussion 444-5. [Content Brief]
