942518-19-6
942518-19-6
Chemical Structure
L-Homopropargylglycine hydrochloride
- CAS No.: 942518-19-6
- Formula:C6H10ClNO2
- Molecular Weight:163.60
IUPAC Name: (S)-2-aminohex-5-ynoic acid hydrochloride
InChIKey: XGBWOGGSQVMSRX-JEDNCBNOSA-N
SMILES: C#CCC[C@H](N)C(O)=O.[H]Cl
Biological Activity: L-Homopropargylglycine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine hydrochloride is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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L-Homopropargylglycine hydrochloride | 98.0% | L-Homopropargylglycine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine hydrochloride is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor. | ||||||||||||||||||||
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References
- [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018;36:553-562. [Content Brief]
- [2]. Shen Y, et al. Protocol for visualizing newly synthesized proteins in primary mouse hepatocytes. STAR Protoc. 2021;2(3):100616. Published 2021 Jun 17. [Content Brief]
