Casein kinase 1δ-IN-29
Casein kinase 1δ-IN-29 (Compound 18) is the inhibitor for p38α and casein kinase 1 that inhibits p38α, CK1δ and CK1ε with IC50 of 0.041 µM, 0.005 µM and 0.447 µM, respectively. Casein kinase 1δ-IN-29 arrests cell cycle at subG1 phase, induces apoptosis in cell AC1-M88.
For research use only. We do not sell to patients.
- CAS No.: 1177418-39-1
- Formula: C26H23FN4O4S
- Molecular Weight:506.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CK1δ 0.005 μM (IC50) |
p38α 0.041 μM (IC50) |
CK1ε 0.447 μM (IC50) |
Chemical Information
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CAS No. 1177418-39-1
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Molecular Weight 506.55
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Formula C26H23FN4O4S
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SMILES
CS(C1=NC(C2=CC=C(C=C2)F)=C(C3=CC=NC(NC(/C=C/C4=C(C=C(C=C4)OC)OC)=O)=C3)N1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)