1177418-39-1
1177418-39-1
Chemical Structure
Casein kinase 1δ-IN-29
- CAS No.: 1177418-39-1
- Formula:C26H23FN4O4S
- Molecular Weight:506.55
SMILES: CS(C1=NC(C2=CC=C(C=C2)F)=C(C3=CC=NC(NC(/C=C/C4=C(C=C(C=C4)OC)OC)=O)=C3)N1)=O
Biological Activity: Casein kinase 1δ-IN-29 (Compound 18) is the inhibitor for p38α and casein kinase 1 that inhibits p38α, CK1δ and CK1ε with IC50 of 0.041 µM, 0.005 µM and 0.447 µM, respectively. Casein kinase 1δ-IN-29 arrests cell cycle at subG1 phase, induces apoptosis in cell AC1-M88[1].
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Casein kinase 1δ-IN-29 | Casein kinase 1δ-IN-29 (Compound 18) is the inhibitor for p38α and casein kinase 1 that inhibits p38α, CK1δ and CK1ε with IC50 of 0.041 µM, 0.005 µM and 0.447 µM, respectively. Casein kinase 1δ-IN-29 arrests cell cycle at subG1 phase, induces apoptosis in cell AC1-M88. | |||||||||||||||||||||
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