Cathepsin L-IN-5
Cathepsin L-IN-5 (D6-3) is a potent Cathepsin L (CatL) inhibitor with an IC50 of 0.27 nM. Cathepsin L-IN-5 effectively blocks the CatL function and substantially hinders the entry of the SARS-CoV-2 pseudovirus to cells by inhibiting the cleavage of the spike protein. Cathepsin L-IN-5 can be utilized in SARS-CoV-2 research.
For research use only. We do not sell to patients.
- Purity: 96.05%
- CAS No.: 3115287-13-0
- Formula: C30H26ClFN2O3
- Molecular Weight:516.99
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Cathepsin Isoforms
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Biological Activity
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cathepsin L 0.27 nM (IC50) |
Chemical Information
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CAS No. 3115287-13-0
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Appearance Solid
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Molecular Weight 516.99
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Formula C30H26ClFN2O3
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Color White to off-white
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SMILES
O=C(C1=C2C=CC=CC2=CC=C1)N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(CCl)=O)=O)CC4=CC=C(C=C4)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 50 mg/mL (96.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.9343 mL | 9.6714 mL | 19.3427 mL | 48.3568 mL |
| 5 mM | 0.3869 mL | 1.9343 mL | 3.8685 mL | 9.6714 mL | |
| 10 mM | 0.1934 mL | 0.9671 mL | 1.9343 mL | 4.8357 mL | |
| 15 mM | 0.1290 mL | 0.6448 mL | 1.2895 mL | 3.2238 mL | |
| 20 mM | 0.0967 mL | 0.4836 mL | 0.9671 mL | 2.4178 mL | |
| 25 mM | 0.0774 mL | 0.3869 mL | 0.7737 mL | 1.9343 mL | |
| 30 mM | 0.0645 mL | 0.3224 mL | 0.6448 mL | 1.6119 mL | |
| 40 mM | 0.0484 mL | 0.2418 mL | 0.4836 mL | 1.2089 mL | |
| 50 mM | 0.0387 mL | 0.1934 mL | 0.3869 mL | 0.9671 mL | |
| 60 mM | 0.0322 mL | 0.1612 mL | 0.3224 mL | 0.8059 mL | |
| 80 mM | 0.0242 mL | 0.1209 mL | 0.2418 mL | 0.6045 mL |
Cathepsin L-IN-5 Related Classifications
HY-169171 Related Classifications
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