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Art. -Nr.: HY-W036566

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2-Phenylcyclopropanamine

2-Phenylcyclopropanamine (Compound 3) is an irreversible inhibitor of MAO-A/B and LSD1. 2-Phenylcyclopropanamine shows no activity against LOXL2.

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Reinheit : 98.83%
CAS. Nr.: 54-97-7
Formel: C₉H₁₁N
Molecular Weight:133.19

Speicherung:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

2-Phenylcyclopropanamine Chemical Structure

CAS. Nr.: 54-97-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

2-Phenylcyclopropanamine (Compound 3) is an irreversible inhibitor of MAO-A/B and LSD1. 2-Phenylcyclopropanamine shows no activity against LOXL2^[1].

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MAO-A
MAO-B

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Cellular Effect

Cell Line	Type	Value	Description	References
HL-60	GI₅₀	553 μM Compound: PCPA	Antiproliferative activity against human HL-60 cells incubated for 3 days by alamar blue assay Antiproliferative activity against human HL-60 cells incubated for 3 days by alamar blue assay	[PMID: 38340642]
HMEC	IC₅₀	1420 μM Compound: PCPA	Cytotoxicity against HMEC cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay Cytotoxicity against HMEC cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay	[PMID: 36262394]
MDA-MB-231	GI₅₀	798 μM Compound: PCPA	Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay	[PMID: 36262394]
LN-18	GI₅₀	303 μM Compound: PCPA	Antiproliferative activity against human LN-18 cells incubated for 3 days by alamar blue assay Antiproliferative activity against human LN-18 cells incubated for 3 days by alamar blue assay	[PMID: 38340642]
PC-3	GI₅₀	559 μM Compound: PCPA	Antiproliferative activity against human PC-3 cells incubated for 3 days by alamar blue assay Antiproliferative activity against human PC-3 cells incubated for 3 days by alamar blue assay	[PMID: 38340642]
PrEC	GI₅₀	1064 μM Compound: PCPA	Cytotoxicity against human PrEC cells incubated for 3 days by alamar blue assay Cytotoxicity against human PrEC cells incubated for 3 days by alamar blue assay	[PMID: 38340642]

Chemical Information

CAS. Nr. 54-97-7
Appearance Solid
Molecular Weight 133.19
Formel C₉H₁₁N
SMILES

NC1CC1C2=CC=CC=C2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Hutchinson JH, et al. Small Molecule Lysyl Oxidase-like 2 (LOXL2) Inhibitors: The Identification of an Inhibitor Selective for LOXL2 over LOX. ACS medicinal chemistry letters. 2017 Apr 13;8(4):423-427. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biologische Aktivität
- Beschreibung
Chemical Information
Reinheit & Dokumentation
Verweise

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2-Phenylcyclopropanamine

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