AChE-IN-101
AChE-IN-101 (Compound 7a) is an AChE inhibitor (IC50s = 0.21 μM (EeAChE); 13 nM (HsAChE)). AChE-IN-101 ameliorates Scopolamine (HY-N0296)-induced cognitive impairment. AChE-IN-101 can be used in the research of Alzheimer's disease.
For research use only. We do not sell to patients.
- Formula: C26H32N4O2
- Molecular Weight:432.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
EeAChE 0.21 μM (IC50) |
Chemical Information
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Molecular Weight 432.56
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Formula C26H32N4O2
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SMILES
CN(C1=CC=C(C(C2=NN(C(C=C2)=O)CCC3CCN(CC3)CC4=CC=CC=C4)=C1)O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)