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Cat. No.: HY-163530

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GPR41 modulator 1

GPR41 modulator 1 (compound 10ak) is a potent GPR41 modulator with an EC₅₀ value of 0.679 µM. GPR41 modulator 1 shows agonistic modulator activity.

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CAS No.: 3050768-93-6
Formule: C₂₈H₂₄F₂N₂O₃
Masse moléculaire:474.50

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

GPR41 modulator 1 Chemical Structure

CAS No.: 3050768-93-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

GPR41 modulator 1 (compound 10ak) is a potent GPR41 modulator with an EC₅₀ value of 0.679 µM. GPR41 modulator 1 shows agonistic modulator activity^[1].

IC₅₀ & Target

EC₅₀: 0.679 µM (GPR41)^[1]

Voir tous les produits spécifiques à Isoform Free Fatty Acid Receptor :

In Vitro

GPR41 modulator 1 (compound 10ak) (1 µM) decreases the cAMP level induced by propionate (10 mM) in HEK293 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3050768-93-6
Masse moléculaire 474.50
Formule C₂₈H₂₄F₂N₂O₃
SMILES

FC1=CC(F)=CC(C2=CC=C(O2)C3C(C(NC4=C(C=CC=C4)C)=O)=C(NC5=C3C(CCC5)=O)C)=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Inuki S, et al. Structure-activity relationship studies of tetrahydroquinolone derivatives as GPR41 modulators. Bioorg Med Chem Lett. 2024 Jul 15;107:129758. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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