Chondroitin sulfate sodium (from bovine)
Based on 1 Customer Validation
Chondroitin sulfate (Chondroitin polysulfate) sodium (from bovine)) is a sulfated linear polysaccharide extracted from bovine sources, belonging to glycosaminoglycans. Chondroitin sulfate sodium (from bovine) inhibits osteoclast-mediated bone resorption and exhibits antioxidant activity, which is negatively correlated with molecular weight. Chondroitin sulfate sodium (from bovine) can be used in studies related to osteoarthritis.
For research use only. We do not sell to patients.
- Purity : 99.40%
- CAS No.: 9082-07-9
- Formula: (C14H21NO14SNa)n
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
Chondroitin sulfate sodium (from bovine) (1-1000 μg/mL; 7 days) reduces the formation of TRAP-positive multinucleated osteoclasts derived from human peripheral blood mononuclear cells only at the concentration of 1000 μg/mL[1].
Chondroitin sulfate sodium (from bovine) (1-1000 μg/mL; 10 days) potently and persistently inhibits the bone resorptive activity of osteoclasts derived from human peripheral blood mononuclear cells[1].
Chondroitin sulfate sodium (from bovine) exhibits concentration-dependent in vitro antioxidant activity. Among these fractions, the lowest molecular weight component (BCS-II-4, 19.7 kDa) shows the strongest scavenging activity against superoxide anions, DPPH radicals and hydroxyl radicals, as well as the highest ferric ion reducing power[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9082-07-9
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Appearance Solid
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Formula (C14H21NO14SNa)n
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Color White to off-white
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SMILES
O=S(O)=O.O=S(O)=O.OC([C@@H]1[C@@H](OC)[C@H](O)[C@@H](O)[C@H](O[C@@H]2[C@@H](NC(C)=O)[C@H](OC)O[C@H](CO[R])[C@@H]2O[R])O1)=O.[Na+].[R].[R].[=].[=].[R2=].[R1=].[n].[or]
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Synonyms
Chondroitin polysulfate sodium (from bovine)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
H2O : 40 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Cantley MD, et al. Comparison of the ability of chondroitin sulfate derived from bovine, fish and pigs to suppress human osteoclast activity in vitro. Inflammopharmacology. 2013;21(6):407-412. [Content Brief]
[2]. Zou Z, et al. Preparation of chondroitin sulfates with different molecular weights from bovine nasal cartilage and their antioxidant activities. Int J Biol Macromol. 2020;152:1047-1055. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chondroitin sulfate sodium (from bovine) Related Classifications
HY-B2162B Related Classifications
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Keywords
- Chondroitin sulfate sodium (from bovine)
- 9082-07-9
- Chondroitin polysulfate sodium (from bovine)
- Free Radical Scavengers
- Reactive Oxygen Species (ROS)
- Endogenous Metabolite
- TRAP-positive multinucleated osteoclasts
- human peripheral blood mononuclear cell-derived osteoclast precursors
- hydroxyl radicals
- osteoarthritis
- human osteoclasts
- NFATc1 transcription factor
- bovine nasal cartilage
- DPPH radicals
- superoxide anions
- tartrate resistant acid phosphatase
- Inhibitor
- inhibitor
- inhibit