Clomipramine hydrochloride (Standard)
Based on 1 Customer Validation
Clomipramine (hydrochloride) (Standard) is the analytical standard of Clomipramine (hydrochloride). This product is intended for research and analytical applications. Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD).
For research use only. We do not sell to patients.
- Purity: 99.31%
- CAS No.: 17321-77-6
- Formula: C19H24Cl2N2
- Molecular Weight:351.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 17321-77-6
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Appearance Solid
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Molecular Weight 351.31
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Formula C19H24Cl2N2
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Color White to off-white
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SMILES
CN(C)CCCN1C2=CC(Cl)=CC=C2CCC3=C1C=CC=C3.Cl
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Synonyms
Chlorimipramine hydrochloride (Standard); G-34586 hydrochloride (Standard); NSC-169865 hydrochloride (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yumi Sugimoto, et al. The tricyclic antidepressant Clomipramine increases plasma glucose levels of mice. J Pharmacol Sci. 2003 Sep;93(1):74-9. [Content Brief]
[2]. Mushtaq Ahmed, et al. Comparative study of the inhibitory effect of antidepressants on cholinesterase activity in Bungarus sindanus (krait) venom, human serum and rat striatum. J Enzyme Inhib Med Chem. 2008 Dec;23(6):912-7. [Content Brief]
[3]. Federica Cavaliere,The tricyclic antidepressant Clomipramine inhibits neuronal autophagic flux. Sci Rep. 2019 Mar 19;9(1):4881. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Clomipramine hydrochloride (Standard)
- 17321-77-6
- Chlorimipramine hydrochloride (Standard)
- G-34586 hydrochloride (Standard)
- NSC-169865 hydrochloride (Standard)
- Reference Standards
- Serotonin Transporter
- Antidepressant
- 5-hydroxytryptamine
- 5-HT
- hyperglycemia
- antidepressant
- 5-HT reuptake
- depression
- obsessive compulsive disorder,OCD
- Inhibitor
- inhibitor
- inhibit