Imipramine hydrochloride (Standard)
Based on 1 Customer Validation
Imipramine (hydrochloride) (Standard) is the analytical standard of Imipramine (hydrochloride). This product is intended for research and analytical applications. Imipramine hydrochloride is an orally active tertiary amine tricyclic antidepressant. Imipramine hydrochloride is a Fascin1 inhibitor with antitumor activities. Imipramine hydrochloride also inhibits serotonin transporter with an IC50 value of 32 nM. Imipramine hydrochloride stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine hydrochloride shows neuroprotective and immunomodulatory effects.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.52%
- CAS No.: 113-52-0
- 화학식: C19H25ClN2
- 분자량:316.87
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- 순도&문서
-
Help & FAQs
-
HY-B0725R
Doxepin Hydrochloride (Standard)Reference Standard -
HY-B0527AR
Amitriptyline hydrochloride (Standard)Stanard of Amitriptyline hydrochloride -
HY-B1287R
Citalopram hydrobromide (Standard) -
HY-B1490
Imipramine hydrochlorideAntidepressant Agent -
HY-B0102AR
Fluoxetine hydrochloride (Standard) -
HY-B0176A
Sertraline hydrochlorideSSRI -
HY-B1272
Desipramine hydrochlorideSerotonin Transporter Inhibitor -
HY-14258A
Escitalopram oxalateSerotonin Reuptake Inhibitor -
HY-B0161A
Duloxetine hydrochlorideSerotonin-norepinephrine Reuptake Inhibitor -
HY-B0457
Clomipramine hydrochloride5-HT Reuptake Inhibitor -
HY-B0196A
Venlafaxine hydrochlorideSerotonin/Norepinephrine Reuptake Inhibitor -
HY-B0161
DuloxetineSerotonin-norepinephrine Reuptake Inhibitor
Product Information
Information
신청
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 113-52-0
-
Appearance Solid
-
분자량 316.87
-
화학식 C19H25ClN2
-
Color White to off-white
-
SMILES
CN(C)CCCN1C2=CC=CC=C2CCC3=CC=CC=C31.[H]Cl
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
-
SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
-
Handling Instructions (2659 KB)
References
[1]. Alburquerque-González B, et al. New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells. Exp Mol Med. 2020 Feb;52(2):281-292. [Content Brief]
[2]. Jeon SH, et al. The tricyclic antidepressant imipramine induces autophagic cell death in U-87MG glioma cells. Biochem Biophys Res Commun. 2011 Sep 23;413(2):311-7. [Content Brief]
[3]. Xia Z, et al. The antidepressants imipramine, clomipramine, and citalopram induce apoptosis in human acute myeloid leukemia HL-60 cells via caspase-3 activation. J Biochem Mol Toxicol. 1999;13(6):338-47. [Content Brief]
[4]. Ramirez K, et al. Imipramine attenuates neuroinflammatory signaling and reverses stress-induced social avoidance. Brain Behav Immun. 2015 May;46:212-20. [Content Brief]
[5]. Balkovetz DF, et al. Evidence for an imipramine-sensitive serotonin transporter in human placental brush-border membranes. J Biol Chem. 1989 Feb 5;264(4):2195-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Imipramine hydrochloride (Standard) Related Classifications
HY-B1490R Related Classifications
Powered by Bioz