Creatine Kinase MB (rCK-MB), Recombinant Human
Based on 1 publication(s) in Google Scholar
Creatine Kinase MB (rCK-MB), Recombinant Human (CK-MB) is a cytoplasmic creatine kinase isoenzyme composed of M and B subunits, belonging to the phosphotransferase family. Creatine Kinase MB (rCK-MB), Recombinant Human catalyzes the transfer of phosphate groups between creatine and phosphocreatine, and consumes phosphocreatine immobilized on the surface of the biosensor, resulting in a decrease in the electrochemical peak current that is proportional to its concentration. Creatine Kinase MB (rCK-MB), Recombinant Human can be used in studies of acute myocardial infarction, coronary artery disease with atherosclerotic plaques, autoimmune myocarditis, and malignant tumors.
For research use only. We do not sell to patients.
- CAS No.: 9001-15-4
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Creatine Kinase MB (rCK-MB), Recombinant Human
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Biological Activity
Description
In Vitro
Creatine Kinase MB (rCK-MB), Recombinant Human (CK-MB) causes a concentration-dependent decrease in the Pcrea peak current, with a limit of detection of 0.11 mg/mL and a polynomial response range of 0.48 to 28.8 mg/mL[1].
Creatine Kinase MB (rCK-MB), Recombinant Human (0.19-28.8 mg/mL; 10 min) interacts with immobilized phosphocreatine on the Pcrea/Cys/Au-SPE biosensor, producing a hyperbolic saturation behavior that conforms to the Michaelis-Menten equation, and exhibits a higher apparent affinity for immobilized Pcrea than for immobilized creatine[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Enzyme Activity
> 400 U/mL
Unit Definition
One unit is defined as the amount of enzyme that catalyze the transphosphorylation of one micromole of phosphate from creatine phosphate to ADP per minute at 37°C
Chemical Information
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CAS No. 9001-15-4
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Creatine Kinase MB (rCK-MB), Recombinant Human]
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Synonyms
CK-MB
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Shipping
Shipping with dry ice.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Autophagy
ESCRT III-mediated lysosomal repair improve renal tubular cell injury in cisplatin-induced AKI. [Abstract]2025 Sep;21(9):1927-1944. PMID: 40152606
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Moreira FT, et al. Novel sensory surface for creatine kinase electrochemical detection. Biosensors & bioelectronics. 2014 Jun 15;56:217-22. [Content Brief]
[4]. Grenadier E, et al. The roles of serum myoglobin, total CPK, and CK-MB isoenzyme in the acute phase of myocardial infarction. American heart journal. 1983 Mar;105(3):408-16. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Creatine Kinase MB (rCK-MB), Recombinant Human Related Classifications
HY-P2799D Related Classifications
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