1. GPCR/G Protein Immunology/Inflammation
  2. CXCR
  3. CXCR2 antagonist 5

CXCR2 antagonist 5 (compound 25) is a potent CXCR2 antagonist. CXCR2 antagonist 5 shows potent CXCR2 binding affinity (IC50=0.013 µM) and calcium mobilization (IC50=0.1 µM)[ 1].

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CXCR2 antagonist 5

CXCR2 antagonist 5 Estructura química

No. CAS : 3037517-09-9

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Descripciòn

CXCR2 antagonist 5 (compound 25) is a potent CXCR2 antagonist. CXCR2 antagonist 5 shows potent CXCR2 binding affinity (IC50=0.013 µM) and calcium mobilization (IC50=0.1 µM)[ 1].

IC50 & Target

CXCR2

0.013 μM (IC50)

Peso molecular

352.36

Fòrmula

C15H14F2N4O2S

No. CAS
SMILES

C[C@@H](NC1=C2C=NOC2=NC(SCC3=CC=CC(F)=C3F)=N1)CO

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
CXCR2 antagonist 5
Cat. No.:
HY-144781
Cantidad:
MCE Japan Authorized Agent: