Cytidine-5'-triphosphate-13C5
Cytidine-5'-triphosphate-13C5 (Cytidine triphosphate-13C5) is the 13C-labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.
For research use only. We do not sell to patients.
- CAS No.: 200258-75-9
- Formula: C413C5H16N3O14P3
- Molecular Weight:488.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 200258-75-9
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Unlabeled Cas 65-47-4
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Molecular Weight 488.12
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Formula C413C5H16N3O14P3
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SMILES
O[13C@H]1[13C@@H](O[13C@@H]([13C@H]1O)[13CH2]OP(OP(OP(O)(O)=O)(O)=O)(O)=O)N2C=CC(N)=NC2=O
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Synonyms
Cytidine triphosphate-13C5; 5'-CTP-13C5; Cytidine-5'-triphosphate-1',2',3',4',5'-13C5 Triethylamine Salt
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Heidy Y Narvaez-Ortiz, et al. A CTP Synthase Undergoing Stage-Specific Spatial Expression Is Essential for the Survival of the Intracellular Parasite Toxoplasma gondii. Front Cell Infect Microbiol. 2018 Mar 22;8:83. [Content Brief]
[2]. Hatch GM, et al., Regulation of cardiolipin biosynthesis in H9c2 cardiac myoblasts by cytidine 5'-triphosphate. J Biol Chem. 1996 Oct 18;271(42):25810-6. [Content Brief]
[3]. Matsumoto S, et al., An equilibrium binding study of the interaction of aspartate transcarbamylase with cytidine 5'-triphosphate and adenosine 5'-triphosphate. Biochemistry. 1973 Mar 27;12(7):1388-94. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)