2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. Datelliptium chloride hydrochloride

Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from Ellipticine (HY-15753). Datelliptium chloride hydrochloride is effective in vivo against a variety of murine solid tumors.

For research use only. We do not sell to patients.

Datelliptium chloride hydrochloride Chemical Structure

Datelliptium chloride hydrochloride Chemical Structure

CAS No. : 157000-76-5

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Datelliptium chloride hydrochloride Related Antibodies

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Description

Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from Ellipticine (HY-15753). Datelliptium chloride hydrochloride is effective in vivo against a variety of murine solid tumors[1][2].

In Vitro

Datelliptium chloride hydrochloride shows cytotoxic effects after 2 hours of treatment in suspension and primary cultures of rat hepatocytes[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Datelliptium chloride hydrochloride Related Antibodies
In Vivo

Datelliptium chloride hydrochloride has broad antitumor activity against solid tumors of mice in vivo[2].
Datelliptium chloride hydrochloride (170 mg/kg; i.v; for 12 days) exhibits a high degree of antitumor activity at early staged disease[2].
Datelliptium chloride hydrochloride is selectively cytotoxic for solid tumors over leukemia L1210[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice, colon adenocarcinoma early staged disease model[2]
Dosage: 170 mg/kg
Administration: Intravenous injection, for 12 days
Result: Showed potent activity against colon adenocarcinoma.
Molecular Weight

434.40

Formula

C23H29Cl2N3O
CAS No.
SMILES

[H]Cl.CC1=C2C(NC3=C2C=C(O)C=C3)=C(C)C4=CC=[N+](CCN(CC)CC)C=C41.[Cl-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Datelliptium chloride hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Datelliptium chloride157000-76-5DNA/RNA SynthesisEllipticineantineoplasticactivityantitumoralhepatotoxicityInhibitorinhibitorinhibit

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Datelliptium chloride hydrochloride
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HY-U00337A
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