1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. Datelliptium chloride hydrochloride

Datelliptium chloride hydrochloride 

Cat. No.: HY-U00337A
Handling Instructions

Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from Ellipticine (HY-15753). Datelliptium chloride hydrochloride is effective in vivo against a variety of murine solid tumors.

For research use only. We do not sell to patients.

Datelliptium chloride hydrochloride Chemical Structure

Datelliptium chloride hydrochloride Chemical Structure

CAS No. : 157000-76-5

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Other In-stock Forms of Datelliptium chloride hydrochloride:

Other Forms of Datelliptium chloride hydrochloride:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from Ellipticine (HY-15753). Datelliptium chloride hydrochloride is effective in vivo against a variety of murine solid tumors[1][2].

In Vitro

Datelliptium chloride hydrochloride shows cytotoxic effects after 2 hours of treatment in suspension and primary cultures of rat hepatocytes[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Datelliptium chloride hydrochloride has broad antitumor activity against solid tumors of mice in vivo[2].
Datelliptium chloride hydrochloride (170 mg/kg; i.v; for 12 days) exhibits a high degree of antitumor activity at early staged disease[2].
Datelliptium chloride hydrochloride is selectively cytotoxic for solid tumors over leukemia L1210[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice, colon adenocarcinoma early staged disease model[2]
Dosage: 170 mg/kg
Administration: Intravenous injection, for 12 days
Result: Highly active against colon adenocarcinoma.
Molecular Weight

434.40

Formula

C₂₃H₂₉Cl₂N₃O

CAS No.

157000-76-5

SMILES

[H]Cl.CC1=C2C(NC3=C2C=C(O)C=C3)=C(C)C4=CC=[N+](CCN(CC)CC)C=C41.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Datelliptium chlorideDNA/RNA SynthesisEllipticineantineoplasticactivityantitumoralhepatotoxicityInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Datelliptium chloride hydrochloride
Cat. No.:
HY-U00337A
Quantity:
MCE Japan Authorized Agent: