BN-81674
BN-81674 is a somatostatin analogue and a selective antagonist of the non-peptide human somatostatin sst3 receptor (Ki=0.92 nM). In addition, BN-81674 reversed the inhibition of cyclic AMP accumulation induced by 1 nM somatostatin through the sst3 receptor with an IC50 value of 0.84 nM. BN-81674 can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 252278-73-2
- Formula: C30H38N4
- Molecular Weight:454.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
SSTR3 0.92 nM (Ki) |
Chemical Information
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CAS No. 252278-73-2
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Molecular Weight 454.65
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Formula C30H38N4
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SMILES
CCCCCC1(N[C@H](CC2=C1NC3=C2C=CC=C3)C4=NC=C(N4)C5=CC=CC=C5)CCCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)