1. Anti-infection
    Metabolic Enzyme/Protease
  2. Bacterial
    HIF/HIF Prolyl-Hydroxylase
  3. Deoxyshikonin

Deoxyshikonin 

Cat. No.: HY-N2187
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Deoxyshikonin is isolated from Lithospermum erythrorhizon Sieb with antitumor activity. Deoxyshikonin increases the expression of VEGF-C and VEGF-A mRNA in HMVEC-dLy, promotes HIF-1α and HIF-1β subunit interaction and binds to specific DNA sequences targeted by HIF, indicates a prolymphangiogenesis as well as a proangiogenesis effect in vitro. Deoxyshikonin shows significant synergic antimicrobial activity with tetracycline against S. pneumonia (MIC=17 μg/mL), also shows significantly inhibitory activities against MRSA.

For research use only. We do not sell to patients.

Deoxyshikonin Chemical Structure

Deoxyshikonin Chemical Structure

CAS No. : 43043-74-9

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Description

Deoxyshikonin is isolated from Lithospermum erythrorhizon Sieb with antitumor activity. Deoxyshikonin increases the expression of VEGF-C and VEGF-A mRNA in HMVEC-dLy, promotes HIF-1α and HIF-1β subunit interaction and binds to specific DNA sequences targeted by HIF, indicates a prolymphangiogenesis as well as a proangiogenesis effect in vitro[1]. Deoxyshikonin shows significant synergic antimicrobial activity with tetracycline against S. pneumonia (MIC=17 μg/mL), also shows significantly inhibitory activities against MRSA[2].

Molecular Weight

272.30

Formula

C₁₆H₁₆O₄

CAS No.

43043-74-9

SMILES

O=C1C(CC/C=C(C)/C)=CC(C2=C1C(O)=CC=C2O)=O

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Deoxyshikonin
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