2. Anti-infection
  3. Bacterial
  4. Diethylamine NONOate diethylammonium salt

Diethylamine NONOate diethylammonium salt  (Synonyms: DEA NONOate diethylamine)

Cat. No.: HY-131925 Pureza: 98.0%
COA
SDS
Instrucciones de manejo Technical Support

Diethylamine NONOate (DEA NONOate, diethylammonium salt) is a nitric oxide donor. Diethylamine NONOate is a potent antimicrobial agent, which can inhibit Escherichia coli growth. Diethylamine NONOate also can enhance preservation of the donor rat heart.

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Diethylamine NONOate diethylammonium salt

Diethylamine NONOate diethylammonium salt Estructura química

No. CAS : 372965-00-9

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 mg En stock
10 mg En stock
25 mg En stock
50 mg En stock
100 mg En stock
200 mg   Obtener un presupuesto  
500 mg   Obtener un presupuesto  

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Diethylamine NONOate diethylammonium salt Related Antibodies

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Descripciòn

Diethylamine NONOate (DEA NONOate, diethylammonium salt) is a nitric oxide donor. Diethylamine NONOate is a potent antimicrobial agent, which can inhibit Escherichia coli growth. Diethylamine NONOate also can enhance preservation of the donor rat heart[1][2].

In Vitro

Diethylamine NONOate (8 and 65 mM; 0-20 h) diethylammonium salt shows the greatest inhibitory effect on E. coli growth at a dose of 65 mM for 20 h, resulting in a 99.9% reduction in E. coli[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Diethylamine NONOate diethylammonium salt Related Antibodies
In Vivo

Diethylamine NONOate (0.1 micromol/L; infused into the coronary circulation; 6 or 12 h) diethylammonium salt enhances the protection of coronary blood flow and cardiac function in isolated rat hearts after storage at 2-3 °C for 12 h[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Peso molecular

206.29

Fòrmula

C8H22N4O2
No. CAS
Appearance

Solid

Color

White to light brown

SMILES

CCNCC.O=NN(O)N(CC)CC
Envío

Shipping with dry ice.
Almacenamiento

-80°C, protect from light, stored under nitrogen
Solvente y solubilidad
In Vitro: 

H2O : ≥ 100 mg/mL (484.75 mM)

DMSO : 100 mg/mL (484.75 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8475 mL 24.2377 mL 48.4754 mL
5 mM 0.9695 mL 4.8475 mL 9.6951 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureza y Documentación

Purity: ≥98.0%

SDS (555 KB)

COA (248 KB) Elemental Analysis Report (107 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 4.8475 mL 24.2377 mL 48.4754 mL 121.1886 mL
5 mM 0.9695 mL 4.8475 mL 9.6951 mL 24.2377 mL
10 mM 0.4848 mL 2.4238 mL 4.8475 mL 12.1189 mL
15 mM 0.3232 mL 1.6158 mL 3.2317 mL 8.0792 mL
20 mM 0.2424 mL 1.2119 mL 2.4238 mL 6.0594 mL
25 mM 0.1939 mL 0.9695 mL 1.9390 mL 4.8475 mL
30 mM 0.1616 mL 0.8079 mL 1.6158 mL 4.0396 mL
40 mM 0.1212 mL 0.6059 mL 1.2119 mL 3.0297 mL
50 mM 0.0970 mL 0.4848 mL 0.9695 mL 2.4238 mL
60 mM 0.0808 mL 0.4040 mL 0.8079 mL 2.0198 mL
80 mM 0.0606 mL 0.3030 mL 0.6059 mL 1.5149 mL
100 mM 0.0485 mL 0.2424 mL 0.4848 mL 1.2119 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Diethylamine NONOate diethylammonium salt Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Diethylamine NONOate diethylammonium372965-00-9DEA NONOateBacterialNO donorAntiviral agentAntimicrobial agentSARS-CoV-2Escherichia coliInhibitorinhibitorinhibit

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Nombre del producto:
Diethylamine NONOate diethylammonium salt
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