372965-00-9
372965-00-9
Chemical Structure
Diethylamine NONOate diethylammonium salt
Synonym(s): DEA NONOate diethylamine
- CAS No.: 372965-00-9
- Formula:C8H22N4O2
- Molecular Weight:206.29
IUPAC Name: N',N'-diethyl-N-hydroxynitrous hydrazide compound with diethylamine (1:1)
InChIKey: LBJLVZKEUWCGIA-UHFFFAOYSA-N
SMILES: CCNCC.O=NN(O)N(CC)CC
Biological Activity: Diethylamine NONOate (DEA NONOate, diethylammonium salt) is a nitric oxide donor. Diethylamine NONOate is a potent antimicrobial agent, which can inhibit Escherichia coli growth. Diethylamine NONOate also can enhance preservation of the donor rat heart[1][2].
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Diethylamine NONOate diethylammonium salt | Diethylamine NONOate (DEA NONOate, diethylammonium salt) is a nitric oxide donor. Diethylamine NONOate is a potent antimicrobial agent, which can inhibit Escherichia coli growth. Diethylamine NONOate also can enhance preservation of the donor rat heart. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.75
HY-134636PAPA NONOate -
Similarity Score 0.74
HY-N189013-(2-Hydroxy-1-methyl-2-nitrosohydrazinyl)-N-methyl-1-propanamine -
Similarity Score 0.73
HY-134216MAHMA NONOate -
Similarity Score 0.72
HY-136278DETA NONOate -
Similarity Score 0.71
HY-126166NOC-5 -
Similarity Score 0.70
HY-N7434RN-Nitrosodiethylamine (Standard) -
Similarity Score 0.69
HY-W540787RN-Nitrosodipropylamine (Standard) -
Similarity Score 0.69
HY-W694629Triethylammonium bicarbonate buffer (1.0M pH 8.5) -
Similarity Score 0.68
HY-131113RN-Nitrosodibutylamine (Standard) -
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References
- [1]. Sysel AM, et al. Antimicrobial properties of diethylamine NONOate, a nitric oxide donor, against Escherichia coli: a pilot study. J Antibiot (Tokyo). 2021 Apr;74(4):260-265. [Content Brief]
- [2]. Du ZY, et al. The nitric oxide donor, diethylamine NONOate, enhances preservation of the donor rat heart. J Heart Lung Transplant. 1998 Nov;17(11):1113-20. [Content Brief]
