2. Disease Areas
  3. Infection
  4. Parasitic Infection
  5. Amebic Infection

Amebic Infection

Amebic infection is a protozoan disease caused by Entamoeba histolytica, leading to severe complications such as amebic liver abscess and potentially affecting other organs via hematogenous spread, with high morbidity and mortality rates predominantly in tropical developing regions including Central and South America, Africa, and the Indian subcontinent.

Amebic Infection (5):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15537
    Tilbroquinol 7175-09-9 98.02%
    Tilbroquinol is an orally active halogenated hydroxyquinoline antiprotozoal agent, mainly used for anti-amoebic infections. Tilbroquinol targets intestinal protozoa and Entamoeba histolytica to eliminate parasites in the intestinal lumen. Tilbroquinol can be used in research related to intestinal infections, intestinal amoebiasis and hepatic amoebiasis.
    Tilbroquinol
  • HY-180343
    FFK29 1795429-46-7
    FFK29 is a synthetic class II histone deacetylase inhibitor (HDACi). FFK29 can potently inhibit the growth and encystation of Acanthamoeba. FFK29 can be studied in research on protozoan and parasitic diseases.
    FFK29
  • HY-B0956A
    Paromomycin 7542-37-2
    Paromomycin (Aminosidine) is an orally active broad-spectrum aminoglycoside aminocyclitol. Paromomycin is produced by Streptomyces riomosus var. Paromomycinus. Paromomycin binding induces local conformational changes in the 16S rRNA A-site. Paromomycin exhibits inhibitory activity against C. parvum. Paromomycin can be used in research related to leishmaniasis, amoebiasis and cryptosporidiosis.
    Paromomycin
  • HY-181643
    YOK24 3075693-57-8
    YOK24 is an orally active MetAP2 inhibitor and anti-amoebic agent. YOK24 binds covalently to MetAP2 and inhibits its peptidase activity, where MetAP2 is a protein essential for the proliferation of *Entamoeba histolytica*. YOK24 can be used in the research of amoebiasis.
    YOK24
  • HY-181644
    NS-181 3075693-63-6
    NS-181 is an orally active MetAP2 inhibitor and antiamebic agent with oral effectiveness.NS-181 functionally inhibits methionine aminopeptidase 2, a protein critical for Entamoeba histolytica proliferation. NS-181 exerts antiamebic activity against Entamoeba histolytica, leading to resolution of amebic liver abscess. NS-181 can be used for the research of amebiasis.
    NS-181