KRIBB11 (Standard)
KRIBB11 (Standard) is the analytical standard of KRIBB11 (HY-100872). This product is intended for research and analytical applications. KRIBB11 is an inhibitor of Heat shock factor 1 (HSF1), with IC50 of 1.2 μM.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 342639-96-7
- Formula: C13H12N6O2
- Molecular Weight:284.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 342639-96-7
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Molecular Weight 284.27
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Formula C13H12N6O2
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SMILES
CNC1=CC=C([N+]([O-])=O)C(NC2=CC3=C(NN=C3)C=C2)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yoon YJ, et al. KRIBB11 inhibits HSP70 synthesis through inhibition of heat shock factor 1 function by impairing the recruitment of positive transcription elongation factor b to the hsp70 promoter. J Biol Chem. 2011 Jan 21;286(3):1737-47 [Content Brief]
[2]. Samarasinghe B, et al. Heat shock factor 1 confers resistance to Hsp90 inhibitors through p62/SQSTM1 expression and promotion of autophagic flux. Biochem Pharmacol. 2014 Feb 1;87(3):445-55 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KRIBB11 (Standard) Related Classifications
HY-100872R Related Classifications
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