Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
CYP2B6
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "CYP2B6" in MCE Product Catalog:
Cat. No.: HY-173465
CAS No.: 2259710-89-7
Target:
Research Areas:
DL5055 (compound 6k) is a potent and selective hCAR activator with an EC50 of 0.35 μM. DL5055 induces CYP2B6 expression and hCAR nuclear translocation in human primary hepatocytes .
Target:
Cat. No.: HY-W140208
CAS No.: 2404-87-7
Target:
Research Areas:
3-Phenylthiophene (Compound 25) is a CYP2A6 inhibitor with a Ki value of 3.3 μM. The Ki values for CYP2E1, CYP2B6, CYP2C9, and CYP2C19 are 9.7, 14, 112, and 107 μM respectively. It shows no significant inhibition on CYP3A4 and CYP2D6. 3-Phenylthiophene can be used in smoking cessation research .
Target:
Cat. No.: HY-17356G
CAS No.: 49562-28-9
Target:
Research Areas:
Mephenytoin (Standard) is the analytical standard of Mephenytoin. This product is intended for research and analytical applications. Mephenytoin, an anticonvulsant, is the CYP2C19 and CYP2B6 substrate .
Cat. No.: HY-W010195R
CAS No.: 877-43-0
Category:
Alkaloids Chrysanthemum × morifolium (Ramat.) Hemsl. Quinoline Alkaloids Plants Umbelliferae
Target:
Cat. No.: HY-110134
CAS No.: 883226-64-0
Target:
Research Areas:
S07662 is a human constitutive androstane receptor (hCAR) inhibitor with an IC50 of 0.7 μM. S07662 recruits the corepressor NCoR in cell-based assays and attenuate the expression of CYP2B6 mRNA in human primary hepatocytes induced by phenytoin (HY-B0448) and CITCO (HY-103244) .
Cat. No.: HY-B1184S1
CAS No.: 1185032-66-9
Cat. No.: HY-B1184S
CAS No.: 1185101-86-3
Cat. No.: HY-B1184S2
Cat. No.: HY-B1184S3
CAS No.: 1261398-53-1
Cat. No.: HY-134522
CAS No.: 2259710-64-8
Target:
Research Areas:
DL5050 is a selective and potent human constitutive androstane receptor (hCAR) agonist that does not activate pregnane X receptor (PXR). DL5050 preferentially induces the expression of CYP2B6 (target of hCAR) over CYP3A4 (target of hPXR) on both the mRNA and protein levels. DL5050 can be used for the researches of cancer and metabolic disease, such as diabetes .
Cat. No.: HY-17356S1
CAS No.: 1092484-57-5
Cat. No.: HY-17356S2
CAS No.: 1261395-55-4
Cat. No.: HY-112142A
CAS No.: 422547-55-5
Synonyms: DVR-23
Target:
Research Areas:
(Rac)-AB-423 (DVR-23) is an anti-HBV candidate compound with promising anti-HBV activity. (Rac)-AB-423 showed no induction of CYP1A2, CYP3A4, or CYP2B6 enzyme activity at high concentrations. (Rac)-AB-423 exhibited desirable pharmacokinetic properties, enabling good systemic exposure and high oral bioavailability. (Rac)-AB-423 achieved more than 2 log viral load reduction in the hydrodynamic injection (HDI) HBV mouse model .
Cat. No.: HY-17459R
CAS No.: 120202-66-6
Synonyms: (S)-(+)-Clopidogrel bisulfate (Standard); (S)-(+)-Clopidogrel hydrogen sulfate (Standard)
Research Areas:
Clopidogrel (hydrogen sulfate) (Standard) is the analytical standard of Clopidogrel (hydrogen sulfate). This product is intended for research and analytical applications. Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively . Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation ．Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor .
Cat. No.: HY-17459S
CAS No.: 1217643-68-9
Synonyms: (S)-(+)-Clopidogrel bisulfate-d3; (S)-(+)-Clopidogrel-d3 hydrogen sulfate
Cat. No.: HY-184864
CAS No.: 2570323-59-8
HIV-IN-16 is a HIV replication inhibitor with an EC50 of 25 pM, and shows no activity in inducing CYP2B6. HIV-IN-16 inhibits HIV replication. HIV-IN-16 can be used in studies related to HIV infection and human immunodeficiency diseases .
Cat. No.: HY-W099758
CAS No.: 105-21-5
Synonyms: γ-Oenantholacton
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
