883226-64-0
883226-64-0
Chemical Structure
S07662
- CAS No.: 883226-64-0
- Formula:C16H16N2O2S
- Molecular Weight:300.38
IUPAC Name: 1-((2-methylbenzofuran-3-yl)methyl)-3-(thiophen-2-ylmethyl)urea
InChIKey: UITFWLJMEZPXOF-UHFFFAOYSA-N
SMILES: O=C(NCC1=C(C)OC2=C1C=CC=C2)NCC3=CC=CS3
Biological Activity: S07662 is a human constitutive androstane receptor (hCAR) inhibitor with an IC50 of 0.7 μM. S07662 recruits the corepressor NCoR in cell-based assays and attenuate the expression of CYP2B6 mRNA in human primary hepatocytes induced by phenytoin (HY-B0448) and CITCO (HY-103244)[1].
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S07662 | S07662 is a human constitutive androstane receptor (hCAR) inhibitor with an IC50 of 0.7 μM. S07662 recruits the corepressor NCoR in cell-based assays and attenuate the expression of CYP2B6 mRNA in human primary hepatocytes induced by phenytoin (HY-B0448) and CITCO (HY-103244). | |||||||||||||||||||||
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