EGFR/VEGFR2-IN-3
EGFR/VEGFR2-IN-3 (compound 9) is a potent EGFR and VEGFR-2 inhibitor with IC50 values of 0.129, 0.142, 3.428 µM for EGFR, VEGFR-2, COX-2, respectively. EGFR/VEGFR2-IN-3 shows cytotoxicity. EGFR/VEGFR2-IN-3 induces apoptosis and cell cycle arrest at G2/M phase.
For research use only. We do not sell to patients.
- CAS No.: 710972-61-5
- Formula: C24H20ClN5O2S2
- Molecular Weight:510.03
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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EGFR 0.129 μM (IC50) |
VEGFR-2 0.142 μM (IC50) |
COX-2 3.428 μM (IC50) |
Chemical Information
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CAS No. 710972-61-5
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Molecular Weight 510.03
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Formula C24H20ClN5O2S2
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SMILES
CC1=CC=C(C=C1)NC(NNC(CSC2=NC3=CC=CC=C3C(N2C4=CC=C(C=C4)Cl)=O)=O)=S
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR/VEGFR2-IN-3 Related Classifications
HY-168655 Related Classifications
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