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Cat. No.: HY-W1061747

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endo-BCN-PEG3 Phosphoramidite

endo-BCN-PEG3 Phosphoramidite is a nucleic acid phosphoramidite modifier containing an endo-bicyclononyne (BCN) group and a PEG3 spacer, enabling site-specific incorporation of endo-BCN-PEG3 into DNA or RNA during solid-phase oligonucleotide synthesis. endo-BCN-PEG3 Phosphoramidite introduces a BCN group that can undergo copper-free strain-promoted azide-alkyne cycloaddition (SPAAC) with azide-containing molecules or inverse electron demand Diels-Alder (IEDDA) reactions with tetrazines, enabling post-synthetic oligonucleotide labeling and bioconjugation.

For research use only. We do not sell to patients.

Formula: C₂₈H₄₈N₃O₇P
Molecular Weight:569.67

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

endo-BCN-PEG3 Phosphoramidite Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
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Bioz

Biological Activity

Description

All DNA/RNA Synthesis Isoforms :

In Vitro

endo-BCN-PEG3 Phosphoramidite enables site-specific incorporation of an endo-BCN group bearing a PEG3 spacer into DNA or RNA during solid-phase oligonucleotide synthesis, allowing the resulting BCN-modified oligonucleotides to undergo copper-free SPAAC with azide-containing molecules or IEDDA reactions with tetrazines for nucleic acid labeling and bioconjugation.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 569.67
Formula C₂₈H₄₈N₃O₇P
SMILES

[H][C@@]1(CCC#CCC2)[C@@]2([H])[C@@H]1COC(NCCOCCOCCOCCOP(N(C(C)C)C(C)C)OCCC#N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.