2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. Estrogen receptor antagonist 8

Estrogen receptor antagonist 8 is a potent ER-antagonist with in vivo anti-uterotrophic potential (EC50 = 4.160 μM).

For research use only. We do not sell to patients.

Estrogen receptor antagonist 8 Chemical Structure

Estrogen receptor antagonist 8 Chemical Structure

CAS No. : 2889370-92-5

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Estrogen receptor antagonist 8 Related Antibodies

Top Publications Citing Use of Products

View All Estrogen Receptor/ERR Isoform Specific Products:

View All Isoforms

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Estrogen receptor antagonist 8 is a potent ER-antagonist with in vivo anti-uterotrophic potential (EC50 = 4.160 μM).

IC50 & Target[1]

Estrogen receptor

 

In Vivo

In an in vivo anti-uterotrophic assay, a dose-response curve set by measuring the reduction of uterus weight of immature female rats when compared to the control group.
Anti-uterotrophic assay of ER-antagonist (compound 4) (s.c.; 1, 3, 10, 20, 30 mg/Kg/day; 3 days) exhibits an excelled anti-uterotrophic potential than TMX (EC50: 7.625 μM), the EC50 value of ER-antagonist 8 is 4.160 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

427.45

Formula

C25H21N3O4
CAS No.
SMILES

COC(C=C1)=CC(CCC2=C3C4=CC=C(C=C4)OC)=C1C2=NN3C5=CC=C([N+]([O-])=O)C=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Estrogen receptor antagonist 8 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Estrogen receptor antagonist 82889370-92-5Estrogen receptor antagonist8Estrogen receptor antagonist-8Estrogen Receptor/ERRInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Estrogen receptor antagonist 8
Cat. No.:
HY-143267
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.