2. Anti-infection
  3. HIV
  4. Fipravirimat dihydrochloride

Fipravirimat dihydrochloride  (Synonyms: GSK3640254 dihydrochloride)

Cat. No.: HY-145569A
Handling Instructions

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Fipravirimat dihydrochloride is a potent HIV-1 inhibitor. Fipravirimat dihydrochloride has the potential for HIV and AIDS research.

For research use only. We do not sell to patients.

Fipravirimat dihydrochloride Chemical Structure

Fipravirimat dihydrochloride Chemical Structure

CAS No. : 2442512-14-1

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1 mg USD 1450 In-stock
5 mg USD 4000 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Fipravirimat dihydrochloride:

Fipravirimat dihydrochloride Related Antibodies

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Description

Fipravirimat dihydrochloride is a potent HIV-1 inhibitor. Fipravirimat dihydrochloride has the potential for HIV and AIDS research[1].

IC50 & Target[1]

HIV-1

 

Clinical Trial
Molecular Weight

799.99

Formula

C43H69Cl2FN2O4S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(CCN1CCN[C@]23[C@@]([C@@H](CC3)C(C)=C)([H])[C@]4([H])[C@@](CC2)([C@]5([C@]([C@@]6([C@@](C(C)(C(C7=CC[C@](C(O)=O)(CF)CC7)=CC6)C)([H])CC5)C)([H])CC4)C)C)(CC1)=O.[H]Cl.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (125.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2500 mL 6.2501 mL 12.5002 mL
5 mM 0.2500 mL 1.2500 mL 2.5000 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2500 mL 6.2501 mL 12.5002 mL 31.2504 mL
5 mM 0.2500 mL 1.2500 mL 2.5000 mL 6.2501 mL
10 mM 0.1250 mL 0.6250 mL 1.2500 mL 3.1250 mL
15 mM 0.0833 mL 0.4167 mL 0.8333 mL 2.0834 mL
20 mM 0.0625 mL 0.3125 mL 0.6250 mL 1.5625 mL
25 mM 0.0500 mL 0.2500 mL 0.5000 mL 1.2500 mL
30 mM 0.0417 mL 0.2083 mL 0.4167 mL 1.0417 mL
40 mM 0.0313 mL 0.1563 mL 0.3125 mL 0.7813 mL
50 mM 0.0250 mL 0.1250 mL 0.2500 mL 0.6250 mL
60 mM 0.0208 mL 0.1042 mL 0.2083 mL 0.5208 mL
80 mM 0.0156 mL 0.0781 mL 0.1563 mL 0.3906 mL
100 mM 0.0125 mL 0.0625 mL 0.1250 mL 0.3125 mL
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Fipravirimat dihydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fipravirimat2442512-14-1GSK3640254GSK 3640254GSK-3640254HIVHuman immunodeficiency virusInhibitorinhibitorinhibit

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