CLZX-205
CLZX-205 (compound C-7) is a selective inhibitor of CDK9, with the IC50 of 2.9 nM. CLZX-205 plays an important role in cancer research.
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- CAS No.: 3033694-01-5
- Formule: C26H30N8O
- Masse moléculaire:470.57
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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CDK9 2.9 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | GI50 |
0.05 μM
Compound: C-7; CLZX-205
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Growth inhibition of human HCT-116 cells incubated for 48 hrs by CCK-8 assay
Growth inhibition of human HCT-116 cells incubated for 48 hrs by CCK-8 assay
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[PMID: 38488882] |
| HT-29 | GI50 |
0.56 μM
Compound: C-7; CLZX-205
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Growth inhibition of human HT-29 cells incubated for 48 hrs by CCK-8 assay
Growth inhibition of human HT-29 cells incubated for 48 hrs by CCK-8 assay
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[PMID: 38488882] |
| SW480 | GI50 |
5.09 μM
Compound: C-7; CLZX-205
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Growth inhibition of human SW480 cells incubated for 48 hrs by CCK-8 assay
Growth inhibition of human SW480 cells incubated for 48 hrs by CCK-8 assay
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[PMID: 38488882] |
Chemical Information
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CAS No. 3033694-01-5
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Masse moléculaire 470.57
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Formule C26H30N8O
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SMILES
CC(N1N=NC2=C1C=C(C3=CC=NC(NC4=CC(C(N5CCCN(CC5)C)=O)=CC=N4)=C3)C=C2)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CLZX-205 Related Classifications
HY-161379 Related Classifications
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