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Referencia número: HY-107677

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A 844606

Name: A 844606
Brand: MedChemExpress
SKU: HY-107677
Price: 400.00 USD
Availability: InStock
Rating: 5 (1 reviews)

A 844606 is a highly potent and selective α4β2 nAChR agonist. A 844606 can be used in the study of schizophrenia, Huntington's disease, Alzheimer's disease, and Parkinson's disease.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 861119-08-6
Fòrmula: C₂₀H₂₀N₂O₂
Peso molecular:320.39

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

A 844606 Chemical Structure

No. CAS: 861119-08-6

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Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
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Actividad biológica

Descripciòn

A 844606 is a highly potent and selective α4β2 nAChR agonist. A 844606 can be used in the study of schizophrenia, Huntington's disease, Alzheimer's disease, and Parkinson's disease^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	>100 μM Compound: 52	Agonist activity at human recombinant alpha3beta4 nAChR in HEK293 cells by FLIPR assay Agonist activity at human recombinant alpha3beta4 nAChR in HEK293 cells by FLIPR assay	[PMID: 22281189]
HEK293	EC₅₀	>100 μM Compound: 52	Agonist activity at human recombinant alpha4beta2 nAChR in HEK293 cells by FLIPR assay Agonist activity at human recombinant alpha4beta2 nAChR in HEK293 cells by FLIPR assay	[PMID: 22281189]
Oocyte	EC₅₀	2.2 μM Compound: 52	Agonist activity at human recombinant alpha7 nAChR expressed in xenopus oocytes by patch clamp assay Agonist activity at human recombinant alpha7 nAChR expressed in xenopus oocytes by patch clamp assay	[PMID: 22281189]

Chemical Information

No. CAS 861119-08-6
Peso molecular 320.39
Fòrmula C₂₀H₂₀N₂O₂
SMILES

O=C1C2=C(OC3=CC=C(N4CC5CN(CC5C4)C)C=C31)C=CC=C2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Leung K. 2-(5-[11C]Methyl-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-xanthene-9-one. 2010 Oct 12 [updated 2011 Jan 19]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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