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Anvatabart

(Synonyms: ARX-788)
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Based on 1 Customer Validation

Anvatabart is an anti-ERBB2 human IgG1 κ monoclonal antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza : 98.15%
  • No. CAS: 2636710-06-8
  • Peso molecular:145.454 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Anvatabart
  • Experimental Validation Results for Anvatabart
  • Experimental Validation Results for Anvatabart
  • Experimental Validation Results for Anvatabart
  • Experimental Validation Results for Anvatabart
  • Anvatabart Chemical Structure
    Anvatabart Chemical Structure
No. CAS: 2636710-06-8
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Anvatabart Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Loaded Anvatabart on AHC2 biosensor, can bind HER2/CD340 Protein, Human (HEK293, His, HY-P70254) with an affinity constant of 1.171E-09 M as determined in BLI assay.

  • 1/16

    Immobilized HER2/CD340 Protein, Human (HEK293, His, HY-P70254) can bind Anvatabart. The EC50 for this effect is 25.9 ng/mL.

  • 1/16

    Flow cytometric analysis of 1×106 MCF-7 cells with Anvatabart (HY-P990697, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Loaded Anvatabart on Sensor Chip Protein A, can bind HER2/CD340 Protein, Human (HEK293, HY-P70254U) with an affinity constant of 1.30E-09 M as determined in SPR assay.

  • Anvatabart Chemical Structure
    1/16
  • Anvatabart
  • Loaded Anvatabart on AHC2 biosensor, can bind HER2/CD340 Protein, Human (HEK293, His, HY-P70254) with an affinity constant of 1.171E-09 M as determined in BLI assay.
  • Immobilized HER2/CD340 Protein, Human (HEK293, His, HY-P70254) can bind Anvatabart. The EC50 for this effect is 25.9 ng/mL.
  • Flow cytometric analysis of 1×106 MCF-7 cells with Anvatabart (HY-P990697, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Loaded Anvatabart on Sensor Chip Protein A, can bind HER2/CD340 Protein, Human (HEK293, HY-P70254U) with an affinity constant of 1.30E-09 M as determined in SPR assay.
  • IgG1-kappa