PLK4-IN-5
PLK4-IN-5 (compound 5f) is a PLK4 (IC50 = 0.8 nM) inhibitor. PLK4-IN-5 can inhibit MCF-7 cell clone formation, induce cell cycle arrest (S/G2 phase), and apoptosis. PLK4-IN-5 has anti proliferative activity against MCF-7 cells (IC50 = 0.48 μM). PLK4-IN-5 can be used in the research of cancer such as breast cancer.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C21H22ClN5O2S2
- Peso molecular:476.01
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Chemical Information
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Peso molecular 476.01
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Fòrmula C21H22ClN5O2S2
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SMILES
NC1=CC=C(C=C1)SC2=NC(NC3=CC=C(C=C3)NC4CCS(=O)(CC4)=O)=NC=C2Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)