TUG-1609
TUG-1609 is a fluorescent tracer targeting free fatty acid receptor 2 (FFA2/GPR43) with a Kd value of 65.1 nM.
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- No. CAS: 2101952-37-6
- Fòrmula: C36H36F3N7O6S
- Peso molecular:751.77
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
TUG-1609 acts as an antagonist of human FFA2 in Flp-In™ T-REx™ 293 cells expressing hFFA2-eYFP, inhibiting propionate-mediated IP1 accumulation with a pIC50 of 6.57[1].
TUG-1609 (2 h) binds to human FFA2 in membrane preparations from Flp-In™ T-REx™ 293 cells expressing hFFA2-eYFP, displacing [3H]-1 with a pKi of 7.31[1].
TUG-1609 (0-500 nM; 2 h) binds to NLuc-tagged human FFA2 in membrane preparations from Flp-In™ T-REx™ 293 cells with a Kd of 65.1 nM, a koff of 0.0249 min-1, and a kon of 368,000 M-1min-1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2101952-37-6
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Peso molecular 751.77
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Fòrmula C36H36F3N7O6S
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SMILES
O=C(CCCN(CC1=CC=C(C(F)(F)F)C=C1)C(C2(C)N(CC2)C(CC3=CSC4=C3C=CC=C4)=O)=O)NCCCNC5=CC=C([N+]([O-])=O)C6=NON=C65
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TUG-1609 Related Classifications
HY-185287 Related Classifications
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